(Download) "Plasma Levels of Brain-Derived Neurotrophic Factor in Obese Women Randomly Assigned to a Very Low-Carbohydrate Diet or an Energy-Restricted Low-Fat Diet" by Christopher James Kemp " Book PDF Kindle ePub Free
eBook details
- Title: Plasma Levels of Brain-Derived Neurotrophic Factor in Obese Women Randomly Assigned to a Very Low-Carbohydrate Diet or an Energy-Restricted Low-Fat Diet
- Author : Christopher James Kemp
- Release Date : January 19, 2013
- Genre: Medical,Books,Professional & Technical,
- Pages : * pages
- Size : 3379 KB
Description
Studies have suggested a role for brain-derived neurotrophic factor (BDNF) in central control of food intake and energy balance. The objective of this study was to assess the effect on circulating BDNF of weight loss in an obese cohort of women. Methods: A cohort of obese women was randomly assigned to: (1) an ad libitum low carbohydrate diet; or (2), a low fat diet with moderate caloric restriction. At baseline, three-months and six-months, height, weight, body fat, and circulating BDNF was recorded. Results: Following weight loss, plasma BDNF showed a marginally significant increase. These data are contrary to the literature, which describes elevated serum BDNF levels in obese subjects compared to normal healthy-weight controls. Conclusions: Weight loss is accompanied by an increase in plasma BDNF, regardless of the macronutrient composition of the diet employed. This effect was more pronounced in subjects assigned to a low carbohydrate diet.
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